Reprogram somatic cells in vivo to restore youthful gene expression patterns without losing cell identity.

Use targeted senolytics or engineered immune cells to selectively eliminate aging-related senescent cells across the body.

Deliver mitochondrial gene replacements or peptide modulators to restore energy production and reduce oxidative damage in aged cells.

Systemically increase Klotho expression through gene therapy to improve cognitive function, kidney health, and cellular resilience.

Identify and administer youthful plasma components (e.g., GDF11, TIMP2) to rejuvenate aged tissues and reset systemic homeostasis.

Repair or replace aged extracellular matrix components to restore tissue elasticity and function in skin, joints, and organs.

Regrow thymic tissue or stimulate thymopoiesis to rebuild a youthful, balanced immune system and reduce inflammation.

Use safe, localized delivery of telomerase-activating agents to extend telomeres in key tissues without increasing cancer risk.